In this case it's not grammatically incorrect, but poor style. "Therefore" binds cause and effect. "As such" binds subjects. ... <看更多>

The use of commas before or after the bindings that give cause and effect, as such, varies according to preference, depending on the flow of the sentence ... ... <看更多>

Therefore ™'s powerful information management solutions safeguard your business information and give you greater productivity, reactivity, ... ... <看更多>

I have always believed that the phrase "as such" (in the meaning "being ... it just means "therefore", like in PIT BULLS ARE DANGEROUS, AND AS SUCH MUST BE ... ... <看更多>