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#1. Cellular and molecular mechanisms of mitochondrial function
由 LD Osellame 著作 · 2012 · 被引用 592 次 — Mitochondria contribute to many processes central to cellular function and dysfunction including calcium signalling, cell growth and differentiation, cell cycle ...
#2. Cellular and molecular mechanisms of mitochondrial function
Mitochondria contribute to many processes central to cellular function and dysfunction including calcium signalling, cell growth and ...
#3. Cellular and molecular mechanisms of mitochondrial function
The synoptic aim of this work was to characterize the molecular function of three genes that are involved in maintaining structural ...
#4. Molecular Machinery and Pathophysiology of Mitochondrial ...
This review discusses the molecular mechanisms of mitochondrial fusion, fission, and physiopathology, emphasizing the biological ...
#5. Cellular and Molecular Mechanisms of ... - Bentham Science
Chain reactions of cardiolipin peroxidation initiated by mitochondrial ROS seem to play a key role in these degenerative processes. Such reactions are ...
#6. Molecular mechanisms and physiological functions of mitophagy
When these cells are shifted from normoxia to hypoxia, mitophagy is induced to decrease mitochondrial quantity, thereby adapting cellular metabolism to ...
#7. Molecular Research on Mitochondrial Dysfunction - MDPI
Mitochondrial diseases disrupt cellular energy production and are among the most complex group of inherited genetic disorders. Affecting approximately 1 in 5000 ...
#8. Mitochondrial dynamics: overview of molecular mechanisms
These balanced dynamic transitions are not only required to ensure mitochondrial function but also to respond to cellular needs by adapting the network to ...
#9. Mechanisms of mitochondrial respiratory adaptation - Nature
Aside from their catabolic functions, mitochondria are central regulators of cell death, govern cellular Ca 2+ levels through sequestration ...
#10. Molecular Mechanisms of Mitochondrial Autophagy/Mitophagy ...
Autophagy is a mechanism of cellular degradation through lysosomes. ... of the molecular mechanisms mediating mitophagy and the role of ...
#11. Molecular mechanisms of lysosome-mitochondria membrane ...
PhD Project - Molecular mechanisms of lysosome-mitochondria membrane contact sites and their role in mitochondrial dysfunction at University ...
#12. Molecular mechanisms and physiologic functions of ...
Mitochondria are double-membrane bound organelles that are essential for numerous cellular processes such as aerobic ATP generation, lipid biosynthesis and haem ...
#13. Cellular and molecular mechanisms of mitochondrial function
摘要：. Mitochondria are membrane bound organelles present in almost all eukaryotic cells. Responsible for orchestrating cellular energy production, ...
#14. The Role of Mitochondria in Cellular Iron–Sulfur Protein ...
The thorough understanding of the diverse biochemical disease phenotypes helps with testing the current working model for the molecular mechanism of Fe/S ...
#15. Molecular bases of mitochondrial disorders - Chacinska - 2021
Information · Mitochondria host diverse metabolic pathways and are key to cellular energy conversion. · Most mitochondrial functions are executed ...
#16. Recent progress in research on molecular mechanisms of ...
Furthermore, it has been shown that autophagy is involved in a wide variety of previously unrecognized cellular functions, such as cell death and metabolism ...
#17. Molecular mechanisms of adipose tissue mitochondrial (mal ...
While there have been studies into the functional changes of mitochondria in obesity, the underlying cellular and molecular mechanisms underlying this ...
#18. The role and mechanism of mitochondrial functions and ...
As mitochondrial functions and energy metabolism are essential for ... with replicative potential: molecular mechanisms controlling cellular ...
#19. Understanding the Molecular Mechanisms of Mitochondrial ...
Understanding the Molecular Mechanisms of Mitochondrial Disease ... for the cellular energy supply through mitochondrial OXPHOS function.
#20. Mitochondrion - Wikipedia
A mitochondrion is a double-membrane-bound organelle found in most eukaryotic organisms. ... In addition to supplying cellular energy, mitochondria are involved in ...
#21. Mechanisms of mitochondrial dynamics
(B, C) Schematic representations of the molecular mechanisms regulating (B) ... mitochondrial division is involved in critical cellular functions including ...
#22. Molecular mechanisms mediating mitochondrial dynamics ...
Mitochondria are essential organelles that produce the cellular energy source, ATP. Dysfunctional mitochondria are involved in the ...
#23. Mitochondrial Mechanisms of Apoptosis and Necroptosis in ...
In addition to playing a pivotal role in cellular energetics and ... the role of mitochondria in cell death and the mechanism that leads to chronic liver ...
#24. Understanding the Cellular and Molecular Mechanisms of ...
role of mitochondria in the mechanisms underlying the benefits ... discoveries that (1) reveal potential novel molecular and cellular.
#25. Investigating the molecular mechanism of mitochondrial ...
We are interested in the dynamic interplay between the intracellular distribution of mitochondria and cellular function. Mitochondria are important not only ...
#26. Determination of Mitochondrial Functional State in Vital ...
Laboratory of Physiology, Molecular and Clinical Pharmacology, ... “Cellular and Molecular Mechanisms of Mitochondrial Function,” Best Practice & Research ...
#27. Molecular and cellular mechanisms regulating mitochondrial ...
Unable to load. Please retry. Grant. Molecular and cellular mechanisms regulating mitochondrial subpopulation dynamics and function in vivo. Funder: National ...
#28. Cellular and Molecular Mechanisms of Photobiomodulation ...
Cytochrome c oxidase, the terminal enzyme of mitochondrial respiratory chain, is considered as the photoacceptor. The mechanisms of ...
#29. Molecular Mechanism of High Glucose Induced Mitochondrial ...
Cellular and Molecular Biology Open Access · Molecular Mechanism of High Glucose Induced Mitochondrial DNA Damage in Retinal Ganglion Cells · Original text.
#30. Mechanisms of mitochondria and autophagy crosstalk
Autophagy is a cellular survival pathway that recycles intracellular ... The molecular mechanism and cellular functions of mitochondrial division.
#31. Mitochondrial Biology in Health and Disease - IMR Press
Interests: mitochondria; bioenergetics; cellular metabolism; F1FO-ATPase; ... The characterization of molecular mechanisms involved in physiological and/or ...
#32. Research - Institut für Biochemie und Molekularbiologie
They play central functions in cellular ATP synthesis, the metabolism of amino ... into mitochondria: molecular mechanisms and regulation of mitochondrial ...
#33. The role of mitochondria in cellular toxicity as a potential drug ...
Thus, we believe that Cell Biology and Toxicology will play a critical role in understanding molecular mechanisms of mitochondria-associated ...
#34. Mitochondrial function and cell size – an allometric relationship
1 MRC Laboratory for Molecular Cell Biology, University College London, ... Cellular allometry, the framework for cell size dependent mitochondrial ...
#35. Mitochondria—hubs for regulating cellular biochemistry
Mitochondria are iconic structures in biochemistry and cell biology, ... how mitochondrial function regulates other cellular responses.
#36. independent coordination of mitochondrial function ... - PLOS
vide a new mechanism by which mitochondrial function and muscle fiber type are concor- ... the Cellular and Molecular Mechanisms of Physical ...
#37. Mitochondrial morphogenesis | University of Helsinki
Mitochondrial function relies on the complex mitochondrial shape, ... Our work focus on the molecular mechanism of mitochondrial membrane architectural ...
#38. Mitochondrial Disease: Clinical Aspects, Molecular ...
Mitochondrial Disease : Clinical Aspects, Molecular Mechanisms, ... DNA and mitochondrial DNA—to maintain standard cellular function.
#39. Molecular Machinery and Pathophysiology of ... - ReadCube
This review discusses the molecular mechanisms of mitochondrial fusion, fission, ... for cellular homeostasis (Wuet al., 2018) and mitochondrial function, ...
#40. Programmed Cell Death: Molecular Mechanisms and ...
Programmed Cell Death: Molecular Mechanisms and Implications for Safety ... or mitochondrial function or assessment of cellular morphology.
#41. Physiological Functions of Mitochondrial Reactive Oxygen ...
Molecular oxygen (O2) is essential for the mitochondrial bioenergetic ... Physiological functions of mitochondrial ROS in diverse cellular processes.
#42. Genetic Basis of Mitochondrial Function and Morphology ...
These data provide a comprehensive picture of the cellular processes and molecular components required for respiratory growth and inheritance of mitochondria ...
#43. Mitochondrial and Cellular Biology – Molecular Cell Therapy
Objectives: To understand the molecular basis of mitochondrial function, ... in patients with mitochondrial disorders, the molecular mechanism generating ...
#44. Research Focus Areas - Mitochondrial Care Research Center
The Mitochondrial Care Research Center at Mayo Clinic has several research focus ... the molecular mechanisms by which mitochondria contribute to cellular ...
#45. Recent advances in the molecular mechanism of...
In addition, the role for mitochondria in cell function has gradually expanded, and its initial identification as the powerhouse for cellular ...
#46. Mitochondria | Encyclopedia MDPI
Mitochondria also play an important role for cell signaling, ... with emphasis on the molecular mechanisms of mitochondrial involvement.
#47. Mitochondrial dysfunction and its role in tissue-specific cellular ...
Keywords: mitochondrial dysfunction, cellular stress, mitochondrial pathology, ... the exact function of the protein and therefore the molecular mechanism ...
#48. Mitochondrial regulation of cell death: a phylogenetically ...
Moreover, mitochondria play a key role in the signal transduction cascades ... and G. Kroemer, "Molecular mechanisms of necroptosis: an ordered cellular ...
#49. Mitochondrial health – essential information for nurses
However, cellular and molecular mechanisms of various diseases that ... The purpose of this article is to review mitochondrial function as a ...
#50. Molecular mechanisms of organ damage in sepsis: an overview
mtDNA - mitochondrial DNA. The mitochondrial respiratory chain is the main source of cellular ROS and at the same time mitochondria are the primary target of ...
#51. Cellular and Molecular Mechanisms of Action of Mitochondria ...
Chain reactions of cardiolipin peroxidation initiated by mitochondrial ROS seem to play a key role in these degenerative processes. Such ...
#52. The role of autophagy in ageing: Molecular mechanisms.
Coordination of mitochondrial biogenesis and degradation is therefore an integral aspect of mitochondria quality control. As such, it regulates both cellular ...
#53. linking the microenvironment, metabolism and the epigenome in
Mitochondrial function and cellular homeostasis ... and the mechanisms that modulate mitochondrial and mtDNA integrity, manifests as reduced development, ...
#54. Mitochondrial Iron in Human Health and Disease
In recent years, cellular and animal models of mitochondrial iron ... Understanding the molecular mechanisms regulating mitochondrial iron pathways will ...
#55. Mitochondria: Form, function, and disease
Also, mitochondria lack the same protective mechanisms found in the nucleus of the cell. However, the majority of mitochondrial diseases are due to mutations in ...
#56. Cellular and molecular mechanisms of mitochondrial function
Cellular and molecular mechanisms of mitochondrial function. Laura D. Osellame, B.Sc (Hons), Ph.D, Research Associate a,b,d,. Thomas S. Blacker, MPhys, ...
#57. Mitochondrial electron transport chain, ROS generation and ...
Mitochondria are a main source of cellular ROS. ... Mitchell P: Possible molecular mechanisms of the protonmotive function of cytochrome ...
#58. Cellular and Molecular Mechanisms of AKI
Formoterol restores mitochondrial and renal function after ischemia-reperfusion injury. Sean R Jesinkey et al., J Am Soc Nephrol, 2014. Onco-Nephrology: Renal ...
#59. Mitochondria: The Cellular Hub of the Dynamic Coordinated ...
These diverse but interconnected mechanisms are found to be critical in the maintenance of a functional, efficient, and responsive mitochondrial population ...
#60. Department of Cellular and Molecular Medicine
Our major goal is to understand the molecular mechanisms that control ... ER-mitochondria cross-talk during ER stress and apoptosis; Role of ...
#61. Molecular and Cellular Biology - Eurac Research
The group activities concentrate on the molecular and cellular mechanisms that ... mutations on mitochondrial morphology, function, and mitochondrial genome ...
#62. 线粒体通透性转变的分子机制和后果 - X-MOL
Molecular mechanisms and consequences of mitochondrial ... reference for the understanding of the mammalian mPTP and its cellular functions.
#63. Cellular and molecular mechanisms underlying presynapse ...
Cellular and molecular mechanisms underlying presynapse formation ... complex functions as an adaptor between kinesin-1 and mitochondria to ...
#64. Mitochondrial form and function in pancreatic β-cells and ...
A variety of cellular parameters may be used as indicators of mitochondrial function, including: the redox state of mitochondrial cytochromes; cellular ATP ...
#65. Cellular and Molecular Metabolism
The image depicts interconnected metabolic pathways and highlights mitochondria as a central hub in cellular metabolism. (Figure by Amy Lin). Home · Cellular ...
#66. Signals and molecular mechanisms of temperature adaptation ...
... of mitochondrial capacities and functions. This thesis sets out to elucidate the cellular signals and molecular mechanism involved in thermal adaptation ...
#67. Mitochondria - Why They're Important and What They Need to ...
The benefits of supporting mitochondrial function are far-reaching for the patient given the many organ systems that are impacted by cellular ...
#68. Molecular mechanisms of human mitochondrial dynamics
Furthermore, no equivalents of Caf4p and Mdv1p have been found in mammalian cells to date. The functions of Fis1 in mammalian cells remain ...
#69. Working Towards a Deeper Understanding of Mitochondria ...
Mitochondria, often referred to as the powerhouse of the cell, are essential for cellular energy production and proper cell function.
#70. Cellular and molecular mechanisms of mitochondrial function
Mitochondria are rod-shaped organelles that can be considered the power generators of the cell, converting oxygen and nutrients into adenosine triphosphate ...
#71. Mitochondria - National Human Genome Research Institute
Mitochondria are membrane-bound cell organelles (mitochondrion, singular) that generate most of the chemical energy needed to power the cell's biochemical ...
#72. Decoding cell death signals in liver inflammation
In this review, we discuss the cellular and molecular mechanisms that ... Indeed, structural and functional alterations of mitochondria have ...
#73. Cellular and molecular mechanobiology
Nuclear mechanotransduction: Forces applied to cells are transmitted all the way to the cell nucleus, where they affect its function. We are studying how this ...
#74. Structure-activity relationships of mitochondria-targeted ... - eLife
Mitochondria also coordinate key cellular processes including lipid ... Progress toward elucidating the molecular mechanism of action (MoA) ...
#75. Cell Biology News - ScienceDaily
Since humans and yeasts have remarkably similar cellular mechanisms, ... that the shape and function of their mitochondria (the powerhouse of cells) is ...
#76. CGG repeat expansion in NOTCH2NLC causes mitochondrial ...
Moreover, idebenone treatment restored mitochondrial function and alleviated ... I. Malik, C. P. Kelley, E. T. Wang, P. K. Todd, Molecular mechanisms ...
#77. Mitochondria - the powerhouses of the cell - Rs' Science
Mitochondrion is a rod-shaped organelle and its function is to generate energy (ATP) for the ... Photo credit: Journal of Molecular and Cellular Cardiology.
#78. Regulation of autoimmune disease progression by Pik3ip1 ...
Metabolic alterations could profoundly affect immune functions and ... However, the detailed mechanisms and their therapeutic potential rem.
#79. Dr Yu-Chiang Lai PhD - University of Birmingham
Director of Mitochondrial Profiling Centre ... We seek to understand the molecular mechanisms that lead to muscle wasting and how exercise is able to ...
#80. For cellular biosynthesis and metabolism, size matters - ASCB
Mitochondrial efficiency is optimal in immortalized human cell lines ... that alter cell function and metabolism to be more or less optimal.
#81. Immune Function Remodeled by Mitochondrial Shape
Dynamic changes in mitochondrial shape link to T cell function. ... of Oncology and the Department of Biochemistry and Molecular Biology.
#82. News - Northwestern University Feinberg School of Medicine
A Northwestern Medicine study has identified a molecular mechanism that helps ... A change in function in a mitochondrial protein is associated with gene ...
#83. Shefali Krishna, PhD - Salk Institute for Biological Studies
Area of Research: Protein homeostasis in mitochondria of post-mitotic tissues during aging and ... Bachelor's degreeCell/Cellular and Molecular Biology.
#84. Chemistry A Molecular Approach 5th Edition | Portal
Now, as the principles and methods of molecular and cellular biology as well as genomic sciences play an ever increasing role in mechanistic ...
#85. Access Free Virtual Karyotyping Answer Key Copy
Parts II-VI comprise a robust collection of protocols for studying different molecular aspects of mitochondrial functions including: genetics and microbiology, ...
#86. m6A-ELISA, a simple method for quantifying N6 ... - bioRxiv
... 10.1101/2022.09.09.507316: Dual role of brain endothelial Gpr126 in ... vaccine boost is associated with a distinct molecular signature.
#87. Cellular and Molecular Basis of Mitochondrial Inheritance: ...
Mitochondrial Disease and Fitness Peter Sutovsky. Preface: A. Mother's. Gift. Mitochondria, the cellular power station organelles, arose from bacterial ...
#88. Molecular Links Between Mitochondrial Damage and Parkinson's ...
The emerging role of nrf2 in mitochondrial function. ... Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative ...
#89. Molecular Mechanisms of Dementia: Biomarkers, ...
The mitochondrial electron transport chain consists of several complexes containing multiple redox centers that normally facilitate transfer of electrons to ...
#90. Biomedical Index to PHS-supported Research
Aseront 505 function PROMO ies to state de The normal i ON A D NTS ... structure and function ( algae ) R37GM - 21337.15 Molecular mechanisms of biological ...
cellular and molecular mechanisms of mitochondrial function 在 Working Towards a Deeper Understanding of Mitochondria ... 的推薦與評價
Mitochondria, often referred to as the powerhouse of the cell, are essential for cellular energy production and proper cell function. ... <看更多>