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#11. AR-42 | 99.03%(HPLC) | Selleck | HDAC inhibitor

Description, AR-42 (HDAC-42) is an HDAC inhibitor with IC50 of 30 nM. Phase 1. · Features, Greater potency relative to SAHA. · Targets. HDAC (Cell-free assay).

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#16. AR-42 (OSU-HDAC42) - BPS Bioscience

AR-42 (also known as OSU-HDAC42), a derivative of hydroxamate-tethered phenylbutyrate is a broad-spectrum deacetylase inhibitor of both histone and ...

#17. AR-42 (OSU-HDAC42) - APExBIO

AR-42 (also known as OSU-HDAC42), a derivative of hydroxamate-tethered phenylbutyrate, is a novel and potent inhibitor of histone deacetylase (HDAC) that ...

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#19. AR-42: Uses, Interactions, Mechanism of Action - DrugBank

AR-42 has been used in trials studying the treatment of Meningioma, Acoustic Neuroma, Testicular Lymphoma, Intraocular Lymphoma, ...

#20. Exploratory Evaluation of AR-42 Histone Deacetylase Inhibitor ...

AR-42 is a small molecule which crosses the blood brain barrier (BBB) in rodents, but the investigators are not certain yet if it will penetrate human VS.

#21. AR42, QS-ZYX-1-61,及erolotinib和MPT0E028併用之抗腫瘤藥 ...

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#23. AR-42 (HDAC-42) | CAS# 935881-37-1 | 2716 - BioVision

AR-42 is a potent histone deacetylase inhibitor (HDACi). It induces growth inhibition, cell- cycle arrest, apoptosis, and activation of caspases-3/7.

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#26. AR-42: A Pan-HDAC Inhibitor with Antitumor and ...

AR-42 : A Pan-HDAC Inhibitor with Antitumor and Antiangiogenic Activities in Esophageal Squamous Cell Carcinoma Yuxuan Zhu,* Ting Yuan,* Yuan ...

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#34. AR-42, a novel HDAC inhibitor, exhibits biologic activity ...

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#38. AR-42 (OSU-HDAC42) HDAC inhibitor,novel and potent

AR-42 is an inhibitor of HDAC with IC50 of 30 nM.

#39. AR42 | HDAC - TargetMol

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#41. Early phase clinical studies of AR‐42, a histone deacetylase ...

AR-42 is an orally bioavailable pan-histone deacetylase inhibitor (HDACi) with tumor inhibitory effects on schwannomas and meningiomas in vitro ...

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#45. (PDF) AR42, a novel histone deacetylase inhibitor, as a ...

AR42 treatment induced cell-cycle arrest at G(2) and apoptosis in both VS and meningioma cells. Also, AR42 exposure decreased phosphorylated Akt in schwannoma ...

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#50. Abstract 119: AR42, a histone deacetylase inhibitor (HDACI ...

Abstract 119: AR42, a histone deacetylase inhibitor (HDACI), increases microRNA (miR)-29b and sensitizes cells to decitabine (DAC) treatment: A ...

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#54. AR-42 直角減速機 - 亞鈦電機

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#55. ar42 - Wisconsin Legislature

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#56. Abstract A Combination of Formoterol and the Histone ...

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#57. Histone deacetylase inhibitor AR‑42 inhibits breast cancer cell ...

AR-42 inhibits the growth of MCF-7 cells by promoting apoptosis. Inhibition of cell growth may be the result of apoptosis, induction of necrosis ...

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#60. Novel histone deacetylase inhibitor AR-42 exhibits antitumor ...

AR-42, a novel HDAC inhibitor, inhibited pancreatic cancer cells by regulating p53 expression, inducing cell cycle arrest, particularly at the ...

#61. Histone deacetylase inhibitor AR-42 and achiral analogues ...

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#64. Effect of AR42 in Primary Vestibular Schwannoma Cells and a ...

HYPOTHESIS AR42, a histone deacetylase (HDAC) inhibitor, reduces viability of primary vestibular schwannoma (VS) cells and delays tumor ...

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#68. AR-42 induces apoptosis in human hepatocellular carcinoma ...

AR-42 is a novel Class I and II HDAC inhibitor that shows cytotoxicity against various human cancer cell lines. The present study aims to ...

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#71. AR-42 | CAS#935881-37-1 | HDAC inhibitor

AR-42, also known as S)-HDAC-42; AR-42; NSC-736012; OSU-42; OSU-HDAC-42; OSUHDAC-42, is a broad-spectrum deacetylase inhibitor of both histone and ...

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#73. Sensitivity of osteosarcoma cells to HDAC inhibitor AR-42 ...

The effect of AR-42 and suberoylanilide hydroxamic acid (SAHA) alone or in combination with doxorubicin on OS cell viability was assessed.

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#76. Effect of AR42 in Primary Vestibular Schwannoma Cells and a...

Hypothesis AR42, a histone deacetylase (HDAC) inhibitor, reduces viability of primary vestibular.

#77. Achiral Derivatives of Hydroxamate AR-42 Potently Inhibit ...

AR-42 is an orally active inhibitor of histone deacetylases (HDACs) in clinical trials for multiple myeloma, leukemia, and lymphoma.

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#80. A phase 1 study of AR-42 in patients with advanced solid ...

2558Background: We have shown that AR-42, an oral pan-histone deacetylase inhibitor, has clinical activity in some hematologic malignancies ...

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#83. AR-42 ((S)-HDAC-42) - Epigenetics - AOBIOUS

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#85. AR-42 - Wikidata

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#96. AR-42 AN-AG0061ZH | CymitQuimica

AR-42. Synonyms: (S)-(+)-N-Hydroxy-4-(3-methyl-2-phenyl-butyrylamino)-benzamide; (S)-(+)-N-Hydroxy-4-(3-methyl-2-phenyl-butyrylamino)benzamide; (S)-HDAC 42 ...

#97. Amidohydrolases—Advances in Research and Application: 2013 ...

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